Featured Blog
Joint Health Supplements: What 20 Years of Clinical Evidence Actually Shows
A look at what the clinical trials on glucosamine, chondroitin, collagen, MSM, and joint-support botanicals actually found — and what the marketing conveniently leaves out.
21
Consecutive Years
ISO-Certified since 2005
11
Active Certifications
Maintained concurrently
4
Pharmacopoeia Markets
USP, EP, JP, CP
Zero
Inspectional Observations
On our FDA site audit
Our Products
Our core portfolio is concentrated on joint-health and connective-tissue ingredients, with adjacent lines in beauty, bone, and pet nutrition. We also offer custom granulation services for tablet manufacturers.
Our Story
Since 2001, HS Biopharma has been a trusted US-based supplier of pharmaceutical-grade joint health raw materials. We partner with FDA-audited, GMP-certified manufacturing facilities to deliver chondroitin sulfate, glucosamine, hyaluronic acid, collagen, and cartilage ingredients that meet the most rigorous quality standards in the industry.
Our commitment to quality, traceability, and regulatory compliance has made us the partner of choice for leading supplement and pharmaceutical manufacturers across North America and beyond.
Learn MoreCommitment to Quality & Compliance
Since achieving ISO certification in 2005, we have maintained an unbroken record of quality and innovation. We identified a critical 5% variance between E-HPLC (enzyme-labeled high-performance liquid chromatography) and CPC (potentiometric titration) in chondroitin sulfate sodium analysis and pioneered its application.
Additionally, HS was the first to control sulfate and chloride levels during manufacturing to meet U.S. Pharmacopoeia standards, ensuring our chondroitin sulfate sodium fully complies with all relevant USP requirements.
NSF-GMP Registered
NSF/ANSI 173 Section 8 · FSMA and 21 CFR Part 111/117 compliant.
Certificate C0117576 (DS 14)
Valid through March 2027
ISO 9001:2015
Quality management system.
Certificate 116526ESTM
Valid through October 2027
ISO 22000:2018
Food safety management system.
Certificate C01FSM01 026041
Valid through October 2027
ISO 14001:2015
Environmental management system.
Certificate 04E 1901 75040
Valid through November 2027
ISO 45001:2018
Occupational health and safety management system.
Certificate 04S 2201 75040
Valid through November 2027
FAMI-QS Certified
Registration FAM-1963 · Specialty feed-ingredient GMP Category K · For animal-nutrition and pet-supplement applications.
Registration FAM-1963
Renewal in process
MSC Chain of Custody
Sustainable marine sourcing for chondroitin and cartilage products from MSC-certified supply chains.
Certificate MSC-C-00382
Valid through February 2026
USFDA Drug Master File
On file with the United States Food and Drug Administration.
DMF 26474 (Chondroitin sulfate)
Active
USFDA Food Facility Registration
Active foreign facility registration for regulated import into the United States.
Registration 19126595900
Expires December 2026
Pharmacopoeia Compliance
USP · EP · JP · CP · Chondroitin sulfate sodium fully compliant with all United States Pharmacopoeia tests.
Registered: US, Ukraine, Brazil, Japan
NASC Preferred Supplier
Listed on NASC Preferred Suppliers directory for chondroitin, glucosamine, hyaluronic acid, and raw materials.
Accepted by NASC Primary Suppliers
HALAL Certified
Covering chondroitin sulfate, collagen, glucosamine, N-acetyl-D-glucosamine, sodium hyaluronate, eggshell membrane, and shark cartilage.
HFC Accreditation Center Hong Kong
Letter of Notification valid through June 2026
Latest Insights
Industry news, regulatory updates, and technical resources for supplement and pharmaceutical manufacturers.
May 8, 2026 · 6 min read
Collagen for Joint Health: Types, Doses, and What the Trials Show
Hydrolyzed collagen peptides and undenatured type II collagen work through entirely different mechanisms. Matching the right type to the right application is the difference between an effective formula and an expensive one.
Ingredients · Science & Evidence
May 2, 2026 · 7 min read
Bovine vs. Porcine vs. Marine Chondroitin: What Actually Differs
Chondroitin sulfate from bovine, porcine, and shark cartilage differs in molecular weight, sulfation pattern, and supply-chain profile. The efficacy differences are smaller than most marketers claim.
Ingredients · Sourcing
April 23, 2026 · 8 min read
Joint Health Supplements: What 20 Years of Clinical Evidence Actually Shows
A look at what the clinical trials on glucosamine, chondroitin, collagen, MSM, and joint-support botanicals actually found — and what the marketing conveniently leaves out.
Joint Health · Science & Evidence